Create and release your Profile on Zintellect – Postdoctoral applicants must create an account and complete a profile in the on-line application system. Please note: your resume/CV may not exceed 2 pages.
Complete your application – Enter the rest of the information required for the IC Postdoc Program Research Opportunity. The application itself contains detailed instructions for each one of these components: availability, citizenship, transcripts, dissertation abstract, publication and presentation plan, and information about your Research Advisor co-applicant.
Additional information about the IC Postdoctoral Research Fellowship Program is available on the program website located at: https://orise.orau.gov/icpostdoc/index.html.
If you have questions, send an email to ICPostdoc@orau.org. Please include the reference code for this opportunity in your email.
Research Topic Description, including Problem Statement:
Genetic engineering technologies are rapidly developing, rendering the manipulation of genetic material increasingly simple, efficient and convenient. This has numerous applications, including the generation of existing naturally occurring pathogens or novel synthetic pathogens de novo from genome assembly techniques, as well as the genetic editing of naturally occurring pathogens to produce synthetic variants. As synthetic biology techniques and methods for manipulating genetic material continue to evolve, it is likely that the technical barrier to genetic engineering will decrease, rendering this approach more accessible to those with less technical expertise or reduced capability. Malicious use of genetic engineering could be used to modulate a range of pathogen characteristics, to enhance pathogenicity, onset and severity of symptoms and environmental persistence. Furthermore, it may be challenging to determine when genetic engineering has been employed, for example when a naturally occurring pathogen is generated de novo in a laboratory setting and used as a bioweapon. As these synthetic pathogens may mimic to an extent the symptoms of wild-type variants, it is plausible that their presence may go unnoticed. The purpose of this research topic is to understand how existing and emerging genetic engineering technologies may be used to create or modify pathogens, and determine what biomarkers may be identified to facilitate the detection of their use.
Example Approaches:
Possible approaches may include:
Relevance to the Intelligence Community:
Synthetic biology is a significant step-forward in the field of genetics and is facilitating breakthroughs in the field of medicine and beyond. However, malicious use of this discipline has a range of potentially harmful, impactful applications. As the underpinning technologies develop, this may allow the modification or generation of pathogens to be carried out more easily, with less technical expertise required. It is therefore vital to know more about how the technologies that currently exist and those that are on the horizon may be applied in the malicious context of a biological attack, how they may alter the impact and how their use can be detected.
Key Words: Pathogen, Synthetic Biology, Genetic Engineering, Molecular Biology, Gene Editing, Detection, Virus
The ORISE GO mobile app helps you stay engaged, connected and informed during your ORISE experience – from application, to offer, through your appointment and even as an ORISE alum!
You gave a rating of 0 star(s)
SECURITY/PRIVACY NOTICE
By continuing to use this system you indicate your awareness of and consent to the following terms and conditions of use. LOGOUT IMMEDIATELY if you do not agree to the conditions stated in this warning.
SECURITY NOTICE
This system is part of a Federal information system. This system is monitored for security purposes to ensure it remains available to all users and to protect information in the system. The system employs software programs to monitor network traffic to identify unauthorized activities. By accessing this system, you are expressly consenting to these monitoring activities. Unauthorized attempts to defeat or circumvent security features; to use the system for other than intended purposes; to deny service to authorized users; to access, obtain, alter, damage, or destroy information; to upload or change information; to otherwise cause system or information damage; or otherwise to interfere with the system or its operation, is prohibited. Evidence of such acts may be dis-closed to law enforcement authorities and result in prosecution under the Computer Fraud and Abuse Act of 1986 and the National Information Infrastructure Protection Act of 1996, or other applicable laws.
PRIVACY NOTICE
This system is for authorized use only. Use of this system constitutes consent to security monitoring and testing. All activity is logged with your host name and IP address. Users (authorized or unauthorized) have no explicit or implicit expectation of privacy. Any or all uses of this system and all files on this system may be intercepted, monitored, recorded, copied, audited, inspected, and dis-closed to authorized site and law enforcement personnel, as well as authorized officials of other agencies, both domestic and foreign. By using this system, the user consents to such interception, monitoring, recording, copying, auditing, inspection, and disclosure at the discretion of authorized site or law enforcement personnel. Unauthorized or improper use of this system may result in administrative disciplinary action and civil and criminal penalties.
You have been inactive on this page for . You will be logged out after 03:00:00.
Select an icon below to visit the website and download an appropriate browser.
For help, please email Zintellect@orau.org.
Question: What is the deadline for submitting an application?
Answer: Not all opportunities have application deadlines. Some opportunities remain open until they are filled. If an opportunity has an application deadline, then it will be listed in the opportunity details or in the opportunity catalog.
Question: How do I reset my password?
Answer: If you have forgotten your password or wish to reset your password, use the "Forgot password or username?" tab on the login to reset it.
Question: I forgot my username. How do I retrieve it?
Answer: Use the "Forgot password or username?" tab on the login. You will receive an email containing your username.
Question: What do I need to submit an application?
Answer: Typically, applicants are required to submit a resume or CV, an official copy of their transcripts or academic record, and a minimum of two references at the time they apply. Additional requirements such as a writing sample, thesis or dissertation, etc. may be required. Review the opportunity details for additional information about the requirements for applying for an opportunity.
Question: Where do I upload my transcripts?
Answer: If required, you will be asked to upload your transcript as a part of the application process.
Question: Where do I submit a writing sample?
Answer: If required, you will be asked to upload a writing sample as part of the application process.
Question: Can a family member serve as a reference?
Answer: No; family members may not serve as references. References must be able to speak to your educational and/or professional experience. At least one academic reference is preferred.
Our Zintellect A.I. is constantly learning how to Match you to our opportunities! So, we want to know when we get it right or when we get it wrong. This will help us make our better! Plus, as a potential applicant to one of our many opportunities across the country, we value you and want to help you on your career path!