Evaluating Transformation Pathways of Organic Chemicals in Natural Environments

Organization
U.S. Environmental Protection Agency (EPA)
Reference Code
EPA-ORD-NERL-SED-2019-03-A
How to Apply

This is a repost of a previous posting. If you previously submitted your application to this reference code without the “-A” at the end, then you do not need to reply. Example: If you applied to “EPA-ORD-NERL-IO-2020-13” you do not need to reapply to “EPA-ORD-NERL-IO-2020-13-A”.

A complete application consists of:

All documents must be in English or include an official English translation.

If you have questions, send an email to EPArpp@orau.org.  Please include the reference code for this opportunity in your email.

Application Deadline
7/31/2020 3:00:00 PM Eastern Time Zone
Description

*Applications will be reviewed on a rolling-basis.

A research opportunity is available at the Environmental Protection Agency (EPA), Office of Research and Development (ORD), National Exposure Research Laboratory (NERL), Systems Exposure Division (SED) in Athens, Georgia.

This research project will focus on characterizing the likely transformation products of organic chemicals due to chemical and biological processes in aquatic, terrestrial and atmospheric systems. These transformations will be represented by reaction schemes associated with specific functional groups that may be present in an organic molecule. The primary objective of the research project is to assemble libraries of transformation pathways affecting the environmental fate of chemical classes that are a priority to the Agency. To accomplish this, data from published/completed experimental studies will be compiled and analyzed to characterize rates of transformation of various chemicals in the natural environment. This data will include the identity of transformation products, the fractional formation of the products, and the observed rates of transformation. The research project will further seek to elucidate the role of ambient conditions (e.g., pH, temperature and turbidity) and the presence of other reactive species in controlling the transformation pathway and reaction kinetics. This data will also form the basis for the  development of Quantitative Structure Activity Relationships (QSARs) based on molecular properties for predicting transformation rates.

With guidance from the mentor, the research participant may be involved in the following training activities:

  • Mining published literature and regulatory documents to extract information on organic chemical transformation pathways that are observed in aquatic ecosystems
  • Synthesizing transformation pathway information from diverse sources to make inferences about the processes controlling chemical transformations
  • Incorporating process science understanding into existing cheminformatics-based software tools for the prediction of organic chemical transformation pathways
  • Developing algorithms to predict rates of transformation from molecular properties, structural attributes, and descriptors of ambient conditions
  • Evaluating the performance of software tools for predicting the identity of the dominant transformation products in natural environments

The research participant will benefit from interactions with an interdisciplinary research team with expertise in chemistry, microbiology, environmental modeling and software engineering. This team is presently working on the development and application of a suite of software tools that will provide the user with predicted reaction pathways, physicochemical properties, and transformation rates for Agency priority organic chemicals. 

Anticipated Appointment Start Date: October 1, 2020

The mentor for this opportunity is Caroline Stevens (stevens.caroline@epa.gov).

This program, administered by ORAU through its contract with the U.S. Department of Energy (DOE) to manage the Oak Ridge Institute for Science and Education (ORISE), was established through an interagency agreement between DOE and EPA. The initial appointment is for one year, but may be renewed upon recommendation of EPA and is contingent on the availability of funds. The participant will receive a monthly stipend commensurate with educational level and experience. Proof of health insurance is required for participation in this program. The appointment is full-time at EPA in the Athens, Georgia, area. Participants do not become employees of EPA, DOE or the program administrator, and there are no employment-related benefits. 

Completion of a successful background investigation by the Office of Personnel Management (OPM) is required for an applicant to be on-boarded at EPA. OPM can complete a background investigation only for individuals, including non-US citizens, who have resided in the US for the past three years.

Qualifications

The qualified candidate should have received a doctoral degree in one of the relevant fields, or be currently pursuing the degree and will reach completion by the start date of the appointment. Degree must have been received within five years of the appointment start date.

Knowledge of organic chemical reaction mechanisms and/or familiarity with cheminformatics software applications is desirable.

Eligibility Requirements
  • Citizenship: U.S. Citizen Only
  • Degree: Doctoral Degree received within the last 60 months or anticipated to be received by 6/1/2020 12:00:00 AM.
  • Discipline(s):
    • Chemistry and Materials Sciences (4 )
    • Computer, Information, and Data Sciences (1 )
    • Earth and Geosciences (3 )
    • Engineering (3 )
    • Environmental and Marine Sciences (4 )
    • Life Health and Medical Sciences (1 )
  • Veteran Status: Veterans Preference, degree received within the last 120 month(s).
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