The Joint Science and Technology Office for Chemical and Biological Defense (JSTO-CBD) Faculty-Student Team defense lab research for Minority Serving Institutions (MIs) is now accepting applications from faculty at Minority Institutions (MI) interested in participating in a 10-week summer research team experience. Faculty applications should include information for one undergraduate student who will join the research team. A separate application must be completed by the named student upon selection of the faculty.
The faculty-student team provides for faculty members of underserved academic communities to team with an undergraduate student for a summer research experience associated with real-world DoD science and technology requirements. This research experience is designed to increase and enhance faculty/student awareness of the mission space and goals of JSTO-CBD and the greater DoD research environment. Faculty and student research teams will conduct research at a Department of Defense lab, normally within commuting distance of a MI. Limited housing allowance may be available for faculty/student teams not within a commuting distance to the research site.
Participant Benefits:
Project Title: Biological Agent (simulant) Detection
Location: Natick, MA
The current state-of-the-art and fastest detection of deleterious bio-agents relies heavily on specific target molecules (antibodies) and genetic sequencing amplification (PCR). The drawbacks to these techniques include lack of environmental stability, production cost, and insufficiently fast response time, and any of these precludes their use in dynamic field environments. Furthermore, engineering attempts to obviate some of these drawbacks encounter production limitations in terms of device fabrication standards. We are attempting to simultaneous overcome these limitations to realize a true fieldable bio-agent sensor by utilizing the following aspects: 1) Antimicrobial peptide (AMP) multiplexed arrays for multi-agent detection; 2) novel data science drive algorithms for fast and accurate detection; 3) self-supported curvilinear 3D printed microfluidic devices with concurrent sensing ligand depositions. We have previously demonstrated the capability of small AMP sensor arrays to discriminate bacterial lipopolysaccharides as well as the performance of 3D printed microfluidic sensor arrays. Herein the objective is to discover new sets of AMP arrays for specific bio-agent targets including viruses, Gram positive bacteria, and biotoxins. The student will be tasked with testing the binding response of existing and new AMP sequences towards select (benign) targets of interest to DTRA using both the 3D printed electrochemical sensors as well as traditional surface plasmon resonance.
Description of duties:
The candidate with work with and receive guidance from both the project lead and CCDC-SC employee as well as the academic collaborators. After appropriate training, independent lab work is expected.
How to Apply
If you have questions, send an email to FSR@orau.org. Please include the name of the Faculty-Student Team in the subject of your email.
Eligibility Requirements
Faculty Eligibility
To be eligible for this program, faculty must: The candidate should have taken general, organic, analytical chemistry, and some biochemistry with demonstrated success in the course lab sections. Experience with electrochemistry and surface plasmon resonance desired but not required. Proficiency in Microsoft Excel expected.
Institution Eligibility Information
Most accredited U.S. post-secondary institutions that meet the statutory criteria for identification as Minority Serving Institutions are listed at: http://www.ed.gov/about/offices/list/ocr/edlite-minorityinst.html
Institutions that meet at least one of the following criteria are eligible:
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